Lionel Messi punished error-prone Chelsea as Barcelona advanced to the Champions League quarter-finals with a 3-0 win at the Nou Camp.
Manchester United's Champions League dreams are over after being rocked by Sevilla, with substitute Wissam Ben Yedder's brace securing a famous win against Jose Mourinho's lacklustre side.
Holders Real Madrid eased into the Champions League quarter-finals with a 2-1 win at 10-man Paris St Germain.
Liverpool eased into the quarter-finals of the Champions League for the first time in nine years with no great alarm in a lifeless goalless draw at home to Porto.
David De Gea's exceptional display saved Manchester United's blushes as Jose Mourinho's men somehow escaped with a goalless draw from a match dominated by Sevilla.
Bayern Munich look assured of a Champions League quarter-final spot for a seventh straight season after thrashing 10-man Besiktas 5-0 in Germany.
Lionel Messi broke his goal duck against Chelsea to deny Antonio Conte's side a crucial lead over Barcelona in their Champions League showdown.
Sadio Mane scored a hat-trick and Mohamed Salah continued his phenomenal run with a 30th of the season as Liverpool won 5-0 at Porto to virtually assure themselves a Champions League quarter-final place.