Man United's qualification hangs in the balance as they couldn't find a way past PSV, Chelsea scored four in Israel, Arsenal kept their hopes alive and Manchester CIty were downed in Turin.
Barcelona, meanwhile, produced one of their best Champions League performances in history.
Watch every goal from Matchday 5.
Alexis Sanchez's double kept Arsenal's hopes of a 16th consecutive knock-out stage qualification alive in their 3-0 Champions League victory over Dinamo Zagreb.
Arsene Wenger laid into his Arsenal team for simply not being good enough after they were thrashed 5-1 by Bayern Munich in Germany. The Gunners boss refused to disclose exactly what he told his players in the dressing room at half-time, when they were already 3-0 down.
Watch highlights from all of this week's Champions League fixtures as Arsenal were hit for five in Munich but the rest of the English contingent sealed wins.
Watch highlights from all of this week's Champions League fixtures in what proved a much more satisfactory couple of nights for the English contingent.
It was a European matchday of two halves for English sides in the Champions League. On Tuesday, stuttering Chelsea were beaten at Jose Mourinho's former club Porto while Arsenal fell to a shock home defeat against Olympiacos. On Wednesday, the Manchester clubs restored some much needed pride with victories against German opposition.
Watch every goal from every game as the 2015/16 Champions League group stages got underway in what turned into a disappointing week for English teams on the whole. Aside from Chelsea brushing aside Maccabi Tel Aviv, there were defeats for Arsenal, Man United and Man City.