Adam Lallana and Phil Jagielka are on for Stewart Downing and Gary Cahill. Craig Gordon, James Morrison and Darren Fletcher replace David Marshall, Chris Martin and Scott Brown.
Wayne Rooney is quickest to react after the ball bounces around in the box, placing a header into the bottom corner.
Mulgrew came across Oxlade-Chamberlain, pushing his elbow into the winger's face.
The home team get the game going. Can Scotland be more of a threat this half?
The Oxlade-Chamberlain header is the difference in a half lacking a lot of quality.