England have kicked off their 2013 Six Nations campaign with a dominant Calcutta Cup victory over Scotland, after an impressive Ireland defeated defending champions Wales in Cardiff.
England ran out 38-18 winners at Twickenham, with tries from Chris Ashton, debutant Billy Twelvetrees, Geoff Parling and Danny Care.
Man of the match Owen Farrell added 18 points with the boot.
Scotland had briefly led when Sean Maitland scored the game's first try after 10 minutes, but England proved too dominant, despite Stuart Hogg adding a second half try for the visitors.
Ireland, meanwhile, began their campaign with a compelling 30-22 victory over the defending Grand Slam champions at the Millennium Stadium.
Tries from Simon Zebo, Cian Healy and Brian O'Driscoll, backed by a strong kicking display from Jonathan Sexton, saw Ireland race to a 30-3 lead in Cardiff early in the second half.
Second half scores from Alex Cuthbert and Leigh Halfpenny threatened a Welsh revival, but the Irish held on to claim the opening win of the championship.
On Sunday, Italy host France in the third fixture of the opening weekend.