Education Secretary Michael Gove led a growing backlash against a pay hike for MPs - telling the regulator that proposed the rise to "stick it".
Mr Gove dismissed the Independent Parliamentary Standards Authority (IPSA) as a "silly organisation" after they proposed an 11% pay increase.
All three main party leaders also condemned the idea of an increase to £74,000 at a time of austerity.
Both Labour's Ed Miliband and Liberal Democrat Nick Clegg pledged to shun the extra money - although David Cameron stopped short of saying the same.
IPSA's chairman Sir Ian Kennedy was defiant over the plans, insisting that politicians' pay had to "catch up" after years of being suppressed.
He said the £4.6 million extra salary costs would be offset by curbs to pensions, "golden goodbyes", and expenses - meaning the overall burden on the taxpayer would only go up by £500,000 when the deal took effect after the 2015 general election.
Sir Ian told ITV News they were "doing something which will last for a generation, not go with the drift of whatever the political wind is".
IPSA has been given the final say on setting pay and pensions for MPs, meaning there would have to be a change in law to block its decisions.
Research by the regulator showed that two-thirds of MPs believe they are underpaid but there is concern about accepting a pay rise amid austerity and with a general election in two years.
Posting on Twitter, Labour's Tom Harris said:
Tory backbencher Douglas Carswell wrote on his blog:
One MP who backed the proposals is Conservative Sir Peter Bottomley who told ITV News: "If an MP is not worth the pay, it is better to change the Member of Parliament".
Users of ITV News' Facebook page had mixed views on the pay hike.