Australia fast bowler Ryan Harris has announced his retirement from all forms of cricket after being ruled out of the Ashes tour by a knee injury.
The 35-year-old, who made his Test debut in 2010, struggled with knee soreness following the first tour match in Kent last week and was replaced in the XI against Essex by Peter Siddle.
Following scans, Harris, who underwent major surgery on his right knee last year and missed the recent Test series in the West Indies due to the birth of his first child, took the difficult decision to call time on his career following 27 Tests and 113 wickets.
"Given the news I received yesterday, and after talking it over with my family, I know now is the right is the time to step away from cricket," Harris said.
Cricket Australia confirmed 22-year-old Pat Cummins will be drafted in to the tour squad as a replacement for Harris, who will remain on for a spell with the group in England.
New South Wales paceman Harris did not break into the Test side until aged 30, playing against New Zealand.
Harris would go on to have a major impact for Australia's attack, notably ripping England apart at Chester-le-Street in 2013 when he finished with career-best Test figures of seven for 117 in the second innings.
He also played 21 one-day internationals, during which he claimed 44 wickets, and made three Twenty20 international appearances.
"I am pretty lucky, I have had a wonderful career and nothing made me prouder than pulling on the Baggy Green," said Harris, who will hold a media conference with Australia captain Michael Clarke following the conclusion of the tour match against Essex at Chelmsford on Saturday.
"I played 27 more Tests than I ever thought I would and I have relished every single moment of them."
Harris paid tribute to his team-mates.
"I couldn't have played with a better bunch of blokes and walking away from the team and our support staff is probably the hardest thing to stomach right now," he added in a statement from Cricket Australia.
"This is a very special team and I know they will do Australia proud in this Ashes series. I know I will certainly be watching every ball."
Harris, whose father was born in Leicester and so could have opted to play for England, hopes to remain involved in the game sometime in the future.
"I am lucky enough to have a wonderful family who have supported me through the ups and downs of my career and I am looking forward to the next chapter of my life with them and spending time with my new son Carter," he said.
"Whatever is next for me, and I don't know what that is right now, I know it will still involve cricket as that is what I love and I want to be able to give back to the game that has given me so much."