"Everyone is entitled to their own opinion, but not to their own facts", said fact-checking organisation Full Fact of ITV's EU referendum debate.
"Thursday's panel took that message to heart, challenging one another over the basic factual building blocks of the opposing cases".
Debating fiercely for the Remain campaign were SNP leader Nicola Sturgeon, shadow business secretary Angela Eagle and Energy and Climate Change secretary Amber Rudd.
Meanwhile, former London Mayor Boris Johnson, former minister Andrea Leadsom and Labour MP Gisela Stuart urged the public to "take back control" and vote in favour of Brexit.
Analysis of Remain and Leave's claims
Fact check round-up: Vote leave claims
- Fact check: 'EU membership costs Britain £350 million a week'
- Fact check: 'EU is lowest zone of growth worldwide'
- Fact check: 'EU law makes it more difficult to deport foreign criminals'
- Fact check: 'Britain outvoted more than other countries in EU'
- Fact check: 'Britain can't scrap VAT on fuel because of EU'
Fact check round-up: Vote remain claims
- Fact check: 'EU memberships strengthens workers' rights'
- Fact check: 'Three million jobs linked to EU relationship'
- Fact check: '50,000 NHS doctors and nurses from EU'
- Fact check: 'Brexit means no guarantee to access single market'
- Fact check: 'NHS boss wants Britain to remain in EU'
- Fact check: 'EU bolsters cross-border crime prevention'
- Fact check: 'Brexit endangers UK union and leaves uncertainty around Irish border'
- Fact check: 'EU membership gives us veto over Turkey membership'