Wayne Rooney is set to make his first Premier League start for Everton in 13 years in Saturday's season opener against Stoke at Goodison Park.
Midfielders Ross Barkley and James McCarthy, whose futures have both been the subject of speculation this summer, are unavailable following groin and knee injuries respectively.
Winger Yannick Bolasie (knee) and defenders Seamus Coleman (broken leg) and Ramiro Funes Mori (knee) will miss the start of the campaign with longer-term problems.
Stoke have a handful of summer signings ready to make their debuts against Everton at Goodison Park.
Darren Fletcher, Kurt Zouma, Josh Tymon and Eric Maxim Choupo-Moting have been brought in by manager Mark Hughes, with all four in contention.
Ibrahim Afellay (knee) and Stephen Ireland (broken leg) are the only absentees as they continue to recover from long-term injuries.
Pickford, Stekelenburg, Martina, Keane, Williams, Jagielka, Baines, Gueye, Schneiderlin, Klaassen, Barry, Davies, Besic, Lennon, Ramirez, Rooney, Calvert-Lewin, Mirallas, Holgate, Lookman.
Butland, Grant, Shawcross, Zouma, Tymon, Johnson, Pieters, Cameron, Fletcher, Adam, Imbula, Choupo-Moting, Allen, Shaqiri, Sobhi, Crouch, Berahino, Diouf, Bony.