- Video report by ITV News Correspondent Geraint Vincent
British and US police have begun investigating separate allegations of sexual assault involving disgraced Hollywood mogul Harvey Weinstein.
The Metropolitan Police are investigating a claim from the 1980s, passed onto them by Merseyside Police.
New York Police are examining a claim from 2004 among allegations that were published in an article in The New Yorker magazine.
The widening scandal has seen Amazon put its studio head Roy Price on an immediate leave of absence amid claims he mishandled allegations against Weinstein.
Actress Rose McGowan has accused Price of failing to take action when she told him she had been raped by the mogul, an assault claim Weinstein denies.
Ms McGowan said that a number of high-profile figures in the industry were aware of Weinstein's predatory behaviour towards women but failed to act.
She also rejected film star Ben Affleck's claims that he did not know what was going on.
"Godd***it! I told him to stop doing that" you said to me face," she wrote.
"The press conf I was made to go to after assault. You lie."
Price also faces separate harassment allegations from an Amazon producer.
Amazon announced it was "reviewing our options for the projects we have with The Weinstein Co", the firm Weinstein founded with his brother Bob and was fired from as the scandal broke.
A string of high-profile female stars have spoken out about alleged sexual assaults by the film executive producer.
Weinstein has "unequivocally denied" any allegations of non-consensual sex.
Kate Beckinsale became the latest to go public with a claim Weinstein behaved inappropriately towards her at a hotel when she was 17.
Meanwhile, The Sun reported pop star turned TV presenter Myleene Klass rejected Weinstein's alleged offer of a "sex contract" at the Cannes Film Festival in 2010.
On Wednesday, Weinstein was filmed in public for the first time, getting into a car which was thought to be taking him to a rehab facility.
The disgraced producer said he was "not doing OK" but "we all make mistakes", as he left what is thought to be his daughter's house in Los Angeles.
Asked how he was, Weinstein said he was "trying my best... I'm not doing OK but I'm trying... I gotta get help. You know what, we all make mistakes ... a second chance, I hope."
The comments came after police were called after a "family dispute" at the home of Weinstein's daughter.
The Los Angeles Police Department (LAPD) confirmed they were called to reports of a "disturbance" at the house but said no crime had been committed. Weinstein was not there when officers arrived.
Regarding the UK and US police investigations, Merseyside Police said it received a report on Wednesday morning alleging a sexual assault had taken place in the London area in the 1980s and referred the matter to Scotland Yard.
A spokesman for the Metropolitan Police said the allegation will be assessed by officers from its Child Abuse and Sexual Offences Command.
The New York Police Department meanwhile confirmed it was investigating claims against Weinstein published in The New Yorker and urged anyone with information to come forward.
Detective Sophia Mason, of the NYPD said: "Based on information referenced in published news reports, the NYPD is conducting a review to determine if there are any additional complaints relating to the Harvey Weinstein matter. No filed complaints have been identified as of this time."
On Wednesday, the Manhattan district attorney's office highlighted failings in an NYPD sting operation in which the 22-year-old model, Ambra Battilana Gutierrez, secretly taped a meeting with Weinstein.
However, the district attorney's office said it decided there was insufficient evidence in the March 2015 recording to prove a crime had taken place.
Sections of the investigation's audio recording were released this week by The New Yorker.
The police reviews and investigations are to take place after a string of women made claims of sexual offences, including rape, against the 65-year-old, who has lost his job and seen his wife leave him amid the scandal.
After the first allegations of sexual harassment emerged, Weinstein issued an apology to the women he had worked with, but stopped short of directly addressing the allegations.
While he has denied many of the allegations against him, Weinstein has issued a vehement denial over three allegations of rape which emerged on Tuesday.
Sallie Hofmeister, a spokesperson for Weinstein, issued a statement on his behalf: "Any allegations of non-consensual sex are unequivocally denied by Mr Weinstein.
"Mr Weinstein has further confirmed that there were never any acts of retaliation against any women for refusing his advances.
"Mr Weinstein has begun counselling, has listened to the community and is pursuing a better path."