Brighton v Chelsea, Saturday 20th January, 12:30pm
Chelsea forwards Pedro and Alvaro Morata are suspended for Saturday's Premier League trip to Brighton following their dismissals against Norwich.
Defender Gary Cahill and playmaker Cesc Fabregas (both hamstring) are again out, with head coach Antonio Conte expected to make changes after giving many fringe players an opportunity in Wednesday's FA Cup win, which went to extra-time and penalties.
Ross Barkley is in the squad and could make his debut off the substitutes' bench, while the Blues have a number of undisclosed doubts.
Steve Sidwell remains Brighton's only injury absentee for the visit of his former club Chelsea.
The midfielder underwent a back operation in September and still faces another few months on the sidelines.
Boss Chris Hughton otherwise has a fully-fit squad as the Seagulls go in search of a first Premier League win in 2018.
Arsenal v Crystal Palace, Saturday 20th January, 3pm
Arsene Wenger insists Alexis Sanchez could feature against Crystal Palace on Saturday despite the Arsenal manager saying a move to Manchester United is "likely" to happen.
Sanchez was left out at Bournemouth as his future remains in doubt, but Wenger could bring him back against the Eagles after he trained with the first team on Friday morning as a potential transfer to Old Trafford rumbles on.
Mesut Ozil is available following a knee problem and defenders Laurent Koscielny and Nacho Monreal (both ankle) are also pushing to return but Olivier Giroud (hamstring) is not in contention while Santi Cazorla (Achilles) is a long-term absentee.
Crystal Palace will be without Ruben Loftus-Cheek who is sidelined with a long-term injury.
Burnley v Manchester United, Saturday 20th January, 3pm
Scott Arfield could return to the Burnley line-up for Saturday's clash with Manchester United after shrugging off a hamstring strain sustained in the New Year's Day defeat to Liverpool.
Arfield's return would be a major boost to Burnley boss Sean Dyche, who will be without striker Jon Walters for up to eight weeks after the 34-year-old underwent knee surgery.
Jose Mourinho will not consider Mkhitaryan for Manchester United's trip to Burnley.
Mkhitaryan will be left out of United's squad for the second straight game while negotiations continue with Arsenal over a swap deal that would see Alexis Sanchez move in the opposite direction.
Ashley Young is back from suspension, though Luke Shaw looks set to retain his place at left-back, with Daley Blind picking up a problem that could rule him out along with Eric Bailly (ankle) and Zlatan Ibrahimovic (knee).
Everton v West Brom, Saturday 20th January, 3pm
Everton new signing Theo Walcott is set for his debut against West Brom on Saturday.
Defender Michael Keane has recovered from a gashed foot that has caused him to miss the last two matches.
Nacer Chadli and James Morrison remain out for West Bromahead of their trip to Everton.
Midfielder Chadli continues to be troubled by a hip problem while Morrison is struggling to shake off a long-term Achilles injury which has wrecked his season.
Jonny Evans is expected to start at Goodison Park on Saturday despite continued speculation about his future, although the Baggies are yet to receive a firm bid for the defender this month.
Leicester v Watford, Saturday 20th January, 3pm
Several players will return to the Leicester team when they resume their Premier League campaign at home to Watford.
Kasper Schmeichel, Harry Maguire, Onyinye Ndidi, Marc Albrighton and Jamie Vardy were all rested to one degree or another against Fleetwood in the FA Cup in midweek but should be back in the starting line-up on Saturday.
Midfielder Tom Cleverley is a doubt for Watford's trip to Leicester in the Premier League on Saturday.
Former Manchester United and Everton midfielder Cleverley went off in the first half of last weekend's 2-2 draw with Southampton with a hamstring problem.
Stoke City v Huddersfield, Saturday 20th January, 3pm
Kostas Stafylidis could make his Stoke debut in Saturday's Premier League home clash with Huddersfield, the Potters' first match with new boss Paul Lambert in charge.
Lambert is assessing the fitness of the Greece left-back signed on loan from Augsburg, with the 24-year-old having last played for the Bundesliga outfit in November.
Fellow defenders Ryan Shawcross, Erik Pieters, Geoff Cameron and Glen Johnson, each of whom have been sidelined, have all trained ahead of the contest at the bet365 Stadium
Huddersfield pair Terence Kongolo and Alex Pritchard are in contention to make their first Premier League starts for the club at Stoke.
Centre-half Kongolo and midfielder Pritchard both stepped off the bench for their league debuts in last week's home defeat to West Ham, while head coach David Wagner has no new injury concerns.
Martin Cranie, Philip Billing and Jon Gorenc Stankovic are edging closer to their returns after injury. Elias Kachunga (knee) remains the only long-term absentee.
West Ham v Bournemouth, Saturday 20th January, 3pm
Forward Javier Hernandez is set to be available for West Ham's Premier League clash against Bournemouth at the London Stadium.
Hernandez, who missed West Ham's Emirates FA Cup replay victory against Shrewsbury on Tuesday, has recovered from flu.
Manager David Moyes will take a late decision on the fitness of Andre Ayew, who is battling a hamstring issue, but Andy Carroll (ankle), Michail Antonio (groin), Jose Fonte (calf), Edimilson Fernandes (ankle) and Winston Reid (groin) are all out.
Josh King and Junior Stanislas are pushing hard to be fit for Bournemouth's Premier League trip to West Ham on Saturday.
Both forwards are continuing to battle hamstring complaints and will be assessed late on ahead of the London Stadium encounter.
Manchester City v Newcastle, Saturday 20th January, 5:30pm
Manchester City have a problem at left-back for Saturday's visit of Newcastle after Fabian Delph (knee) joined the injury list.
Delph, who had been covering for long-term casualty Benjamin Mendy (knee) could be sidelined for at least a few weeks. Other options include Danilo and youngster Oleksandr Zinchenko.
Striker Aleksandar Mitrovic could return to the Newcastle squad for Saturday's Premier League trip to Manchester City.
The Serbia international has missed the last eight games with a back injury, but has returned to training and will hope to be involved at the Etihad Stadium.
Defenders Jesus Gamez (ankle) and Florian Lejeune (foot) are improving, but are not yet ready to return.
Swansea v Liverpool, Monday 22nd January, 8pm
Swansea are waiting on striker Tammy Abraham ahead of Monday's Premier League home game with Liverpool.
The England international has missed four games with a hip injury, but the return of Wilfried Bony from a hamstring problem has bolstered Swansea's strikeforce.
Mike Van der Hoorn (muscle injury), Renato Sanches (hamstring) and Angel Rangel (calf) should all be available.
Liverpool top scorer Mohamed Salah and defenders Dejan Lovren and Ragnar Klavan are all expected to recover from illness to face Swansea on Monday.
Centre-back Virgil van Dijk returns to the side after a tight hamstring ruled him out of last week's win over Manchester City.
Captain Jordan Henderson (hamstring) and Alberto Moreno (ankle) are back in training but are not likely to be ready until next weekend's FA Cup tie at home to West Brom.