Scientist have confirmed an unmanned Falcon 9 rocket blasted off from Cape Canaveral Air Force Station in Florida deliver a cargo ship to the International Space Station for NASA.
The 208-foot tall booster, built and launched by privately owned Space Exploration Technologies, bolted off its seaside launch pad at 5.52am GMT, slicing the night-time sky with a bright plume of light as it headed into orbit.
Ten minutes later, the Dragon cargo capsule perched on top of the rocket was released to begin a two-day journey to the space station, a $100 billion research complex that flies about 260 miles above Earth.
Later tonight, a Nasa spacecraft is expected to reach Mars.
A charity has said family doctors need to be able to spot more cases of blood cancer at an earlier stage.
Leukaemia Care said GPs need better knowledge of blood cancers such as leukaemia so they can help diagnose patients when their cancer is at an earlier stage.
More than half of patients with the condition are only diagnosed after they have gone to hospital as an emergency case, the charity said.
This often means that their cancer is at a more advanced stage and can be harder to treat.
Iran is willing to work with the US to help defeat Islamic State (IS) militants, a senior Iranian government source has told Reuters.
However, Tehran would like to see more flexibility over its nuclear programme in exchange for helping Western powers tackle IS.
"Iran is a very influential country in the region and can help in the fight against the ISIL (IS) terrorists ... but it is a two-way street. You give something, you take something," the source was quoted as saying.
However, a Western diplomatic source said the countries negotiating over Tehran's nuclear programme were "determined not to bring the other subjects to the nuclear negotiations table".
David Cameron has been accused of engaging in "panicky and ill-considered bargaining" during the Scottish referendum campaign.
Writing in the Sunday Times, Former minister David Davis claimed the UK's political leadership had "behaved with remarkable carelessness" towards the interests of voters in the UK.
Mr Davis said it was "disgraceful" that the people of England, Wales and Northern Ireland had not been consulted about the plans.
He also called for the instant removal of Scottish MPs' right to vote on English issues - an issue David Cameron has vowed to address.
"Both logic and justice demand that the first step in the process, the removal of Scottish MPs' right to vote on English business, should happen straight away," Mr Davis wrote.
He also suggests no new powers should be transferred to Scotland until a "complete deal, debated and scrutinised by parliament for the whole of the UK".
Former environment secretary Owen Paterson has criticised David Cameron over his handling of the Scottish referendum.
Mr Paterson - who was sacked as environment secretary during July's government reshuffle - told the Sunday Times MPs were left "in the dark" about what was going to be offered to Scotland in a bid to keep the union together.
He also claimed that the Prime Minister did not discuss the details of the referendum with the Cabinet.
“I have talked to two cabinet ministers, one of them still serving, as to whether the detail of this referendum was discussed in cabinet and I don’t remember it being so,” Mr Paterson said.
Nick Clegg has warned the Prime Minister not to link the issues of a new "English votes for English laws" with his promise of further powers for Scotland.
Writing in the Sunday Times, Mr Clegg accused the Tories of being more concerned with the threat from Ukip than the vow made to Scotland.
"The Conservatives, in their rush to protect themselves from an attack from the right, are only concerned about English votes on English matters.
"Of course we need a solution to this dilemma but, by appearing to link it to the delivery of further devolution to Scotland, they risk reneging on the commitment made to the Scottish people that, in the event of a No vote, new powers would come what may."
The Deputy Prime Minister said there could be "no ifs, no buts" about delivering extra powers to Scotland, adding that the package "cannot be made contingent on other constitutional reforms".
David Cameron has called on Ed Miliband to work with him to ensure only English MPs can vote on English laws.
Promising to deliver a "truly fair settlement for the whole of the UK", the Prime Minister urged the Labour leader to help address the "fundamentally unjust" situation which means Scottish MPs can vote on laws which do not apply to their constituents.
Writing in the Mail on Sunday, Mr Cameron said if Miliband did not agree, he should explain to the British people "why they shouldn't have the same powers as we are rightfully devolving to the people of Scotland".
"Why should Scottish MPs be able to vote on what is taught in English schools, to reduce spending on English hospitals, or even vary English or Welsh income taxes, when under the new settlement English or Welsh MPs would have no say in such matters in Scotland?" Mr Cameron said.
Meanwhile, Mr Cameron said a timetable for giving Scotland a new range of powers over tax, spending and welfare would be met, after Alex Salmond accused Westminster of "tricking" No voters.
A British woman who went missing while travelling on a yacht off the coast of Mexico has been found dead.
The Foreign Office confirmed that a body, believed to be that of Simone Wood, was discovered following a search operation launched in the wake of Hurricane Odile.
Ms Wood's partner Paul Whitehouse is still missing, Associated Press reported.
"We can confirm the death of a British national, reported missing along with another British national earlier this week off the coast of Mexico," a Foreign Office spokeswoman said.
An intruder who made it into the White House after breaching security was allegedly armed with a knife, a court document has revealed.
Oscar Gonzalez, 42, climbed over the fence and made it through an entrance to the White House on Friday night - just minutes after President Obama and his daughters had left the presidential residence.
Gonzalez was charged with unlawfully entering a restricted building or grounds while carrying a "deadly or dangerous weapon," the US Attorney's Office said.
The Secret Service previously said Gonzalez was unarmed.
Sir Richard Branson has been voted Britain's most admired business leader.
The Virgin boss was was the runaway winner in the survey of FTSE 100 and FTSE 250 chairmen, chief executives, lawyers, accountants and headhunters.
Branson was recognised for his "longevity and impact across a big number of industries."
Among the runners up in the poll, published today in the Sunday Times, was the vacuum cleaner designer Sir James Dyson.