After a tricky two years pushing his controversial health reforms through Parliament, the South Cambridgeshire MP Andrew Lansley has lost his job as Health Secretary.
He will stay in the Cabinet, moving to the role of Leader of the House. But it is a move Mr Lansley is unlikely to be pleased with - he has always talked about his passion for the health brief, and is said to have visited every hospital in the country during his time as Health Secretary and before that as Shadow Health Secretary.
It is also a job Andrew Lansley has held for a long time for the Conservatives. In opposition he was Shadow Health Secretary for 6 years before becoming Health Secretary when the Coalition Government came to power in 2010.
The health reforms that passed through Parliament just a few months ago were very much his idea and he was passionate about the need for NHS reform, even though the proposals were greatly criticised by some medical professionals and Liberal Democrat parliamentary colleagues.
There were question marks over Andrew Lansley's job last year when the NHS reforms proved so controversial that the legislation was paused during its parliamentary process to allow the Government to "listen' to what medical professionals were saying. But the reforms completed their parliamentary passage, and the South Cambridgeshire MP will be disappointed not to remain as Health Secretary to see the reforms actually put into place in the NHS.
For live updates on the Cabinet reshuffle visit ITV News' national pages: http://www.itv.com/news/