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Madeline Reeder from Lowestoft in Suffolk is not even 4-years old yet and already she has had 17 operations.
She has a medical condition so rare that only 7 people in the world's population of seven billion have it.
Her a chromosomal abnormality is so rare it doesn't even have a name. The nearest experts can get is "X13 mosaic unbalance translocation".
Madeline was born with life-threatening problems with her intestines, a heart defect and a cleft palate. She's also at risk of developing eye cancer.
Madeline has to be fed directly into her stomach by a tube and is currently unable to eat.
Madeline's mum Sammy is now training to run the London Marathon next month, to raise money for Genetic Disorders UK.
A Radio station Manager who was first on the scene of a house fire in Luton has been speaking to ITV News Anglia about the blaze.
Mohammed Tariq from Inspire FM in Luton, was passing the house in Runley Road when he saw the smoke coming from the roof of the building.
Mohammed Tariq said. "I stopped the car and saw a gentleman coming in and out of the house...he was very dazed, I had to make sure there was nobody else upstairs. There was a neighbour too and I made sure they were safe."
Suffolk police have named the man found in water off the coast of Lowestoft on Monday afternoon, as 43-year old Peter Chambers from Wellesley Road in Great Yarmouth.
Police have still not been able to trace his next-of-kin.
Enquiries are continuing into what happened on behalf of the Coroner and Suffolk police continue to lead the investigation.
It's now known the boat that Mr Chambers was on, left Great Yarmouth harbour on Monday morning for a fishing trip.
Two men from Great Yarmouth have been reported missing.
One of the two missing men is in his 40s, the other in his late 70s.
The boat recovered from the water has been examined and police have taken calls from people who reportedly saw the boat in rough seas between Gorleston and Lowestoft.
A new report has revealed that children are watching up to four hours of TV a day.
It also found that children are watching more live television instead of the "on demand" services that are now on offer.
Click above to watch this report from Katie Rowlett.
The rising price of a first class stamp is something that causes concern for many people and businesses who still send a lot of letters.
Now a Cambridgeshire businessman has decided to expand his newspaper delivery round to include a new postal service.
Brian Webb from Wisbech is offering to deliver post for his current newspaper customers at a cost of 30 pence a stamp, half the price of Royal Mail.
Brian Webb has been delivering newspapers around Wisbech for 50 years and say he wanted to offer another service to his customers.
Click above to watch a report by ITV News Anglia's Stuart Leithes, who joined Brian on his early morning round.
A prolific shoplifter has been banned from entering shops in Huntingdon town centre.
41-year-old Christian Jordan has been given a Criminal anti-social behaviour order or CRASBO, which bans him from all stores in the town.
Jordan who has 30 shoplifting convictions, admitted theft and three counts of common assault at Huntingdon magistrates last month.
The case was a joint investigation between police and Huntingdon Business Against Crime.
PC Emma Tavener said. "Jordan is a prolific shoplifter who has been offending for more than 10 years. This kind of offending is not a victimless crime as businesses have to invest in extra security and those costs are inevitably passed on to shoppers.
This Crasbo gives us an extra tool in dealing with Jordan and hopefully give him some structure to start to prevent his offending."
The order will run until August 2015.
Norfolk Fire Service has confirmed that a fire station which burned down on Tuesday morning wasn't fitted with sprinklers.
The retained station at Downham Market was destroyed along with a new vehicle inside. The damage has been estimated around two million pounds.
The county's deputy chief fire officer said the service should have followed its own advice.
The station currently has a new engine which is being kept at the police station, next door to the destroyed fire station.
Two men have been arrested after a police chase in Norwich last night. It happened after a till was stolen from a post office in Freethorpe.
A Vauxhall car matching the description of one seen leaving the post office was then reported leaving a petrol station without paying.
The men were eventually arrested in the area of Reepham Road after the police gave chase.
Police are expected to name the man who was pulled from the water following a boating incident off the Suffolk coast, later today.
The man who was from Great Yarmouth, was on a fishing trip from Gorleston in Norfolk, when their boat overturned on Monday afternoon.
Two other men are still unaccounted for.