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They've been credited with increasing the chances of surviving a serious injury by up to 20 percent.
But charities like the East Anglian Air Ambulance and Essex and Herts Air Ambulance receive no government funding, and rely entirely on donations to keep going.
Jonathan Wills and Elodie Harper spoke to Diana Jakubowska from the East Anglian Air Ambulance about how they manage to fund their work and keep flying.
How do charities like the East Anglian Air Ambulance and the Essex and Herts Air Ambulance stay flying when neither receive any government funding?
ITV News has been taking a close look at the work of our Air Ambulance teams.