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It has a world-wide reputation for medical excellence, pioneering life-saving operations, and first-class research.
From carrying out the world's first heart lung and liver transplant to the UK's first use of an artificial heart, Papworth Hospital has been at the forefront of surgery techniques.
As the Cambridgeshire hospital welcomes its new boss, we take a look back at its impressive history.
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Papworth Hospital's chairman says its move to a new Cambridge site will help it become the "world class centre" the UK needs.