Live updates

Cancer risk test could boost screening programme

Research by Cambridge scientists could lead to routine tests for patients genetic risk of cancer within five years.

The study compared the DNA of more than 100,000 cancer patients with a similarly sized sample from the general population.

They used microchip technology capable of identifying more than 200,000 genetic variants, some of which were suspected of being linked to cancer.

More than 1,000 scientists from 130 institutions in Europe and the US took part in the Collaborative Oncological Gene-environment Study (Cogs).

We're on the verge of being able to use our knowledge of these genetic variations to develop tests that could complement breast cancer screening and take us a step closer to having an effective prostate cancer screening programme

– Professor Doug Easton - Cancer Research UK

Dr Harpal Kumar, chief executive of Cancer Research UK, which co-funded the research, said:

This groundbreaking international work highlights how complex cancer is.

Hundreds, if not thousands of genes are likely to play a role in how cancers start.

But by understanding why some people seem to be at greater risk of developing cancer we can look towards an era where we can identify them and take steps to reduce their chances of getting cancer or pick up the disease at its earliest stages."

Scientists look for the secrets of youth

by Martin Stew

Scientists are trying to solve a question which some spend thousands trying to achieve - the secret of growing old gracefully.

Experts at The Sanger Institute in Cambridge have been looking at DNA changes in identical twins.

By comparing the siblings they found certain age genes that are switched on or off by environmental and lifestyle factors.

Advertisement

Advertisement

Today's top stories