Northampton Saints star Courtney Lawes has been dropped from the England squad to face Ireland at Twickenham.
Lawes misses out in favour of Saracens' Maro Itoje.
It means that Lawes, can play in Northampton's Aviva Premiership clash with Worcester on Saturday.
England Squad: Forwards D Cole (Leicester Tigers), J Clifford (Harlequins), J George (Saracens), D Hartley (Northampton Saints, capt), J Haskell (Wasps), P Hill (Northampton Saints), M Itoje (Saracens), G Kruis (Saracens), J Launchbury (Wasps), J Marler (Harlequins), C Robshaw (Harlequins), B Vunipola (Saracens), M Vunipola (Saracens).
Backs: M Brown (Harlequins), D Care (Harlequins), E Daly (Wasps), O Farrell (Saracens), G Ford (Bath Rugby), A Goode (Saracens), J Joseph (Bath Rugby), J Nowell (Exeter Chiefs), A Watson (Bath Rugby), B Youngs (Leicester Tigers).
Northampton Saints centre Luther Burrell has been recalled to the England squad ahead of this weekend's Six Nations clash with Ireland.
The call-up marks a return to the international fold for the 28-year-old, who was famously dropped from the World Cup squad at the last minute by former coach Stuart Lancaster.
Burrell admitted the rejection left him "broken" and was subsequently given time off by the Saints to get over the blow.
However, he will now have a chance to impress new boss Eddie Jones after Bath's Ollie Devoto was ruled out with concussion.
The new North Stand at Northampton Saints' Franklin's Gardens will be officially opened today (February 13).
The 2,000-seater Barwell Stand has been used since early November but a ceremonial cutting of ribbon will take place this afternoon before Saints' Premiership clash with London Irish.
The day will be dedicated to the Barwell family who have played a key role in the running of the club in recent years.
A number of Saints legends will also be paraded in front of the crowd before kick-off.
"Although the Barwell Stand will honour the name for years to come, it is only fitting that supporters are given the opportunity to show their gratitude and thanks to Keith and the rest of the Barwell family for what they have done for Saints over the years which has culminated in us being where we are today - one of the best clubs in England.
One of Keith's core beliefs was that the club is bigger than any one individual, which is why we're inviting players who have put their names in the history books by having played hundreds of times in the first team to join us, and why we're working with local schools to tell youngsters about our past that we're so proud of.
It will be a great occasion, and we're looking forward to seeing another full house to help make this a memorable day for Keith and his family."
Northampton Saints v London Irish, Aviva Premiership, Saturday 13 February, 15:00
Four players have the Anglia region have been named in new coach Eddie Jones' first 33-man England squad.
Dylan Hartley, Paul Hill and Courtney Lawes of Northampton Saints and Norfolk's Ben Youngs of Leicester Tigers are in the squad.
No captain named at this stage but Dylan Hartley is widely tipped despite his disciplinary problems. The Northampton hooker, 29, was dropped from the World Cup squad after a series of disciplinary breaches.
The notable omissions from the squad is Ben's brother Tom Youngs, the Leicester hooker who has been dropped and Northampton Saints' Tom Wood.
England head coach Eddie Jones says he has "chosen a lot of new players on the growth we see in them".
"The long-term strategy for England is to develop a side who can be the most dominant team in world rugby. Jones says "the door is not shut for anyone" after naming his first squad.
“I have spoken to some of the players who have not been selected," he said. "Naturally they will be disappointed and that is how it should be. They know what they need to do to get back into this squad.
"There is no such thing as a shut door because of injuries and loss of form. There will always be opportunities to anyone playing consistently well in the Premiership and Europe.”
The squad will meet at Pennyhill Park on 24 January to prepare for their opening Six Nations match against Scotland in Edinburgh on Saturday 6 February.
Alex Corbisiero has left Northampton Saints with immediate effect, the club has announced.Read the full story ›
Alex Corbisiero has left Northampton Saints with immediate effect, the club has announced.
Northampton Saints got 2016 off to the perfect start this afternoon beating Premiership title rivals Exeter Chiefs 8-3 in front of a record crowd at Franklin's Gardens.
Saints Hooker Mark Haywood got the only try of game in the first half. As the rain poured down the home side held firm and although Exeter scored a penalty with seven minutes to go, Northampton always looked like claiming a well deserved victory.
Northampton Saints will hoping to bounce back from their shock Boxing Day defeat at London Irish when they host Exeter Chiefs today (January 1).
The Chiefs are currently second in the Aviva Premiership and everyone involved with Saints knows they'll have to be at their best to win.
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Northampton Saints could make an official complaint after England made an approach for their backs coach Alex King.Read the full story ›
Northampton Saints forward Alex Corbisiero has announced he is going to take a break from rugby at the end of the season.
The England prop has suffered a series of injuries in recent years and missed the World Cup this autumn with a back problem.
Corbisiero's contract at Franklin's Gardens expires in the summer and he says that instead of looking for a new club, he will take a year-long sabbatical instead.