Milton Keynes athlete Chris Clarke, the guide runner for blind sprinter Libby Clegg win Gold in the Women's T11 100 metres.
The pair won the race in a photo finish, winning in 11.96 secs - just two 100ths of a second ahead of the Chinese athlete Guohua Zhou and her guide Dengpu Jia.
Teenage swimmer Ellie Robinson kept the ParalympicsGB Gold Rush going with a dominant display in the pool.
The 15-year-old from Northampton was the fastest qualifier in the women's S6 50 metres butterfly.
And the youngster continued that form in the final- storming to a Paralympic record of 35.58 seconds.
Speaking after the race she told Channel 4 she couldn't believe she'd won:
"I keep looking round to check, Oh My God it's so weird. I gave it everything I just maxed it and put everything I'd done into training into that race."
Cambridgeshre's Jody Cundy overcame his disappointment of missing out on a medal in London to take Gold in the C4 1K time trial.
Cundy who's from Wisbech powered home in a new Paralympic record.
School children at Northampton High School have been celebrating after their fellow pupil Ellie Robinson qualified for tonight's S6 50m Butterfly final at the Paralympics.
The 15-year-old won her heat with ease to make it through to tonight's showpiece in Rio.
Suffolk powerlifter Zoe Newson has added another medal to her collection after winning bronze in the -45kg category in Rio this afternoon.
The 24-year-old, who has dwarfism, claimed Paralympic bronze in the 40kg in London four years ago and achieved the same feat this time out.
China's Hu Dandan won the gold, while Nigeria's Latifat Tijani finished second.
Teenage Northampton swimmer Ellie Robinson has qualified fastest for tonight's S6 50m Butterfly final at the Paralympics.
The 15-year-old, who has Perthes hip disease, finished first in her heat in Rio with an impressive time of 36.62 seconds.
The final is expected to take place at around 22:20 tonight.
Huntingdon swimmer Harriet Lee has claimed silver in the SB9 100m breaststroke at the Paralympics.
The 25-year-old, who has Beckwith-Wiedemann syndrome, won bronze in the same category in London four years ago.
Lee produced a brilliant swim to record a personal best of 1min 16.87sec in Rio to finish second.
The gold went to Holland's Lisa Kruger who was about a second ahead.
Thanks everyone for the amazing support last night ❤ I'm so pleased to have made the podium after the last months https://t.co/uCSmzYs7Nv
Great Yarmouth swimmer Jessica-Jane Applegate has thanked her fans for their "amazing" support after she won a bronze medal on the first day of the Paralympics.
The 20-year-old finished third in the S14 100m backstroke, with teammate Bethany Firth claiming gold.
Applegate has Asperger syndrome and next goes in the S14 200m Freestyle heats on Sunday.
Norfolk swimmer Jessica Jane Applegate has won bronze in the 100 metre backstroke S14 category at the Olympic Aquatics stadium during the first day of the games.
The 20-year-old from Great Yarmouth won a gold at the London 2012 game.
Great Britain's Bethany Firth won gold.
Meanwhile sprinter Jonnie Peacock set a new Paralympic record of 10.81secs in the T44 100m heat.
He'll go for gold in the final tonight.
There's just a few hours until the Opening Ceremony for the Paralympics will begin, so who are the athletes in the East to look out for?Read the full story ›