The NHS Blood and Transplant Service says almost half the donors in the East are aged 45 or over and they need to encourage more young people to roll up their sleeves and start giving.
With hospitals across the country using 7,000 units of blood every 24 hours the service needs to attract 1,000 new donors each day to keep stocks sustainable.
Click below to watch a report by ITV News Anglia's Serena Sandhu:
More top news
There will be a few wintry showers tonight but tomorrow will see some sunny spells.
A man from Northamptonshire has begun an epic journey, to walk 5500 miles from his home town of Kettering to Mount Kilimanjaro in Africa.
There's a big change in the race for promotion from the Championship, as Norwich take the advantage after winning the East Anglia Derby.