The NHS Blood and Transplant Service says almost half the donors in the East are aged 45 or over and they need to encourage more young people to roll up their sleeves and start giving.
With hospitals across the country using 7,000 units of blood every 24 hours the service needs to attract 1,000 new donors each day to keep stocks sustainable.
Click below to watch a report by ITV News Anglia's Serena Sandhu:
More top news
Rain this evening with showers expected tomorrow and minimum temperatures overnight of 9 deg C 9 66 deg F)
Early fog will clear to leave a dry day with sunny spells and highs of 18 deg C (64 deg F)
Overnight there'll be mist and fog but it will clear for Sunday leaving sunny spells.