Thousands of women are being contacted after a health care worker at two hospitals in the region discovered they had Hepatitis C.
The worker was based at Bedford Hospital for around six weeks during 1978. They also spent five days at Stamford hospital in 1983.
More than three thousand women are being contacted across England and Wales at the 11 different hospitals they worked at.
So far two women are known to have developed the virus. Stamford and Bedford hospitals say patients that could have been exposed are being contacted.
There is also a national helpline number. Bedford Hospital added that the risk of getting the virus through surgical contact is very low.