Today is Jeans for Genes Day and people across the region have been wearing their denim to raise money for genetic research.
It's those developments that the family of little Florie-Rae from Hertfordshire are hoping will provide a breakthrough. The 3-year-old suffers from Rett Syndrome.
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A 54-year-old man has died and another has been taken to hospital after a group of swimmers got caught up in a riptide at a Norfolk beach.
It will be a dry and warm night with some clear spells and light winds. Lows of 15 deg C (59 deg F).
Two men who tried to abduct an RAF serviceman in Norfolk may have been part of a larger team, it has been revealed.