Today is Jeans for Genes Day and people across the region have been wearing their denim to raise money for genetic research.
It's those developments that the family of little Florie-Rae from Hertfordshire are hoping will provide a breakthrough. The 3-year-old suffers from Rett Syndrome.
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Cloudy and breezy, with persistent and occasionally heavy rain. This rain may stick in the east, western areas may see some late brightness.
Cloudy with more rain. This rain will become increasingly heavy and persistent during the early hours to give a wet start to Sunday
Ice hockey rivals from Peterborough and Milton Keynes prepare for their local derby match with an unusual challenge away from the rink.