Today is Jeans for Genes Day and people across the region have been wearing their denim to raise money for genetic research.
It's those developments that the family of little Florie-Rae from Hertfordshire are hoping will provide a breakthrough. The 3-year-old suffers from Rett Syndrome.
More top news
The Duke and Duchess of Cambridge have been seen for the first time in public with both their children at Sandringham.
Any remaining heavy showers should clear to leave a dry night. Lows of 12 deg C.
Princess Charlotte will have five godparents - two less than her brother Prince George. This is who the royal couple have chosen.