Stadium MK will host England Under-21's crucial UEFA European qualifier against Finland, the Football Association have announced.
The game will take place on Thursday 14 November, with a 19:45 kick-off.
It will be the third time that the home of MK Dons has staged an Under-21 international, following fixtures with Bulgaria and Azerbaijan in 2007 and 2009 respectively.
The Young Lions, who are likely to include Norwich City's Nathan Redmond in their squad, currently trail Finland by four points in Group 1 but victory in Buckinghamshire would go a long way to reducing that deficit.
England also travel to another one of the region's grounds, Ipswich Town's Portman Road, on Tuesday 15 October when they host Lithuania.
England Under-21s boss Gareth Southgate told the Football Association's website that home advantage could allow his team to take control of the Group:
“It’s always good to be back on home soil for our qualifiers and hopefully we can get the results we want from these matches.
“It’s a busy start to the qualifying campaign for us, but we want to try and be in control of the group going into next year.
“We’re spoilt with the pitches that we get to play on here in England so we’ll be looking forward to these games.”
Ticket details for the clash at Stadium MK are listed on the club's official website.