The East of England Ambulance service says 2 patients have been seriously injured in the A1 coach crash at Diddington.
It says they were taken to Addenbrooke's Hospital while a further eleven patients were taken to Hinchingbrooke Hospital with minor injuries.
The trust sent five ambulance crews and three rapid response vehicles to the scene.
More top news
A High Court judge has stepped in to save the Christmas Wonderland at Clacton in Essex from being closed down.
The East of England Ambulance service is facing one of its busiest days of the year.
Christmas can be agony for parents whose children have been missing for years.