New figures have revealed towns and cities in this region could be among the hardest hit by the proposed HS2 rail link.
The report suggests businesses will leave places like Norfolk, Essex and Cambridgeshire, and relocate to other areas with better links to the high speed train line.
It could cost the economy in the East hundreds of millions of pounds.
Click below to watch Tanya Mercer's report.
More top news
More than 4,600 academics have signed a letter calling for an inquiry into the death of PhD student Giulio Regeni in Cairo last month.
A Norfolk patient has become the first woman in the world to have a so-called 'dead kidney' transplant thanks to new technology.
As the number of whales dying on our beaches rises, we've spoken to an Evolutionary Biologist about why this tragic event keeps happening.