New figures have revealed towns and cities in this region could be among the hardest hit by the proposed HS2 rail link.
The report suggests businesses will leave places like Norfolk, Essex and Cambridgeshire, and relocate to other areas with better links to the high speed train line.
It could cost the economy in the East hundreds of millions of pounds.
Click below to watch Tanya Mercer's report.
More top news
Police are appealing for information following the disappearance of one of the UK's rarest birds of prey in the Great Bircham area.
Unemployment in the East of England fell by 13,000 in the three months to July, official figures have revealed.
After a murky start most inland areas will brighten up, although low cloud may linger near the coast.