It has a world-wide reputation for medical excellence, pioneering life-saving operations, and first-class research.
From carrying out the world's first heart lung and liver transplant to the UK's first use of an artificial heart, Papworth Hospital has been at the forefront of surgery techniques.
As the Cambridgeshire hospital welcomes its new boss, we take a look back at its impressive history.
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The family of a teenager who was stabbed to death as he walked home from college in Chelmsford say they are inconsolable.
Dry and chilly overnight. Winds strengthening Sunday and becoming milder.
Dry with some sunshine but a cold wind.