It has a world-wide reputation for medical excellence, pioneering life-saving operations, and first-class research.
From carrying out the world's first heart lung and liver transplant to the UK's first use of an artificial heart, Papworth Hospital has been at the forefront of surgery techniques.
As the Cambridgeshire hospital welcomes its new boss, we take a look back at its impressive history.
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Turning very cold and frosty overnight. Temperatures will drop to around minus 4. A few showers may affect the coast of Norfolk.
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It will take time for the temperatures to climb in the morning but it will be a dry but cold day with plenty of sunshine.