It has a world-wide reputation for medical excellence, pioneering life-saving operations, and first-class research.
From carrying out the world's first heart lung and liver transplant to the UK's first use of an artificial heart, Papworth Hospital has been at the forefront of surgery techniques.
As the Cambridgeshire hospital welcomes its new boss, we take a look back at its impressive history.
More top news
There'll be plenty of sunshine during the rest of today but, unfortunately, the unsettled weather returns this weekend.
The Cator children, from Ranworth in Norfolk are staging the global run in honour of their dad Charlie who has a rare form of cancer.
Following a wet Thursday, today will be drier and brighter with plenty of sunshine.