Part of the A11 is still closed after a crash involving two cars and a lorry near Mildenhall.
Police, fire and air ambulance services are still at the scene and a woman is believed to have suffered serious injuries.
The collision happened shortly after 11am.
The stretch of road between the Fiveways roundabout and the Elveden crossroads has been closed.
Diversions are in place, but drivers have been warned to expect major delays.
More top news
Tributes have been pouring in for a woman who died in a house fire in West Norfolk.
Any residual evening showers should die out. Clear spells at first, and turning chilly in places. Lows of 9 deg C (48 deg F).
A woman has died in a house fire in Heacham in West Norfolk.