US pharmaceutical giant Pfizer could make a hostile bid for AstraZeneca as early as today.
Its £63 billion takeover offer was rejected after the UK company said it "substantially" undervalued the business.
That has forced Pfizer to consider its next move, with industry experts believing a hostile bid - which would aim to bypass the AstraZeneca management and target shareholders directly - could come soon.
Last week, Pfizer insisted it was committed to building a research and development hub in Cambridge which was planned by AstraZeneca.
The £300m base at the Cambridge Biomedial Campus would house about 2,000 researchers.
But a hostile bid would trigger increased calls for the offer to be referred to the competition authorities and would also heighten union fears over jobs if the takeover was successful.
More top news
Saturday will be largely cloudy with a continued risk of heavy showers or thunderstorms. Sunday will be dry with sunny spells.
There continues to be a risk of thunder tonight and tomorrow but the weather will become drier and clearer by sunday.
The Chief Exec of car manufacturer Lotus has said he is deeply sorry to announce job losses at the company's head quarters in Norfolk.