Former Cabinet minister Andrew Lansley has announced he is stepping down from Parliament at the general election and hopes to get an "international" role.
In a letter to David Cameron, the South Cambridgeshire MP said he told the Prime Minister earlier this year that he would not be seeking re-election.
"You supported my ambition to continue my life of public service in challenging and important roles," he wrote. "I am grateful to you now for expressing your support for me to take such a role in international public service in the months ahead."
The missive does not make clear what post Mr Lansley, who was replaced as Leader of the House of Commons by William Hague, is referring to.
There had been widespread speculation that he could be nominated as the UK's next European commissioner, but Mr Cameron disclosed today that the former Leader of the Lords, Lord Hill, had been put forward.
In his response to Mr Lansley, the premier wrote: "You have much more to give in terms of public service, and I look forward to being able to support you in doing so in the months and years ahead."
Andrew Lansley leaves the top table of politics after a decade by leaving the Cabinet and announcing he will step down as an MP next year.
David Cameron has carried out the biggest wholesale shake-up of his ministerial team since becoming Prime Minister.
Liz Truss is one of the fastest-rising stars of the 2010 intake of Conservative MPs, reaching the Cabinet at the age of just 38.