The Hemel Hempstead MP Mike Penning has been appointed a Home Office minister while the Grantham & Stamford MP Nick Boles is now the joint Minister of State at the Business and Education departments.
Mr Boles will have the implementation of equal marriage as part of his new brief. He was the junior minister in the Communities and Local Government minister.
Mr Penning was the Minister for Disabled People and has been a Northern Ireland minister and a Transport minister. He is a former firefighter.
Andrew Lansley leaves the top table of politics after a decade by leaving the Cabinet and announcing he will step down as an MP next year.
David Cameron has carried out the biggest wholesale shake-up of his ministerial team since becoming Prime Minister.
Liz Truss is one of the fastest-rising stars of the 2010 intake of Conservative MPs, reaching the Cabinet at the age of just 38.