The Eastern region has the highest life expectancy in England, according to a study published in The Lancet medical journal.
Men in affluent areas of the East of England can expect to live to an average age of 83, eight years longer than men in deprived areas of the North West.
Women in the least deprived areas live to an average of 85 compared to 79 in the most deprived areas, the study has found.
Despite large health inequalities, England has overtaken many western countries, such as Norway, Canada, France, the Netherlands and Spain, for average life expectancy of men.
Each region in England has seen a rise of at least six years in life expectancy, which is largely down to a fall in cardiovascular disease and cancer deaths.
Across England people are expected to live to an average of 81 compared to 75 in 1990.
The study was co-authored by Professor Rupert Bourne of Anglia Ruskin University. It was funded by the Bill and Melinda Gates Foundation and Public Health England.