Two people have died after a one-vehicle crash on the A711 near Dumfries last night.
The crash happened at around 9.52pm and police are appealing for witnesses.
Two HGV's have been involved in a crash on the M6 Junction 40 slip road at Penrith.
Officers were called at 1.47pm to the incident on the northbound entry slip road.
The slip road is now completely closed and delays are to be expected for some time.
The lanes heading west on the A66 have also been reduced and traffic is slow moving.
Emergency services are at the scene and motorists are asked to avoid the area.
Hail, sleet and snow showers are expected to become frequent overnight and at first on Tuesday morning.
Heavier snowfall is likely to affect higher level routes where 2-5 cm of snow may accumulate in places, whilst 1 to 2 cm is possible to lower levels.
Some transport routes may be affected, with journeys requiring longer travel times.
Two people have died in a one-vehicle crash on the A711 near to Tower Wood in Dumfries.
The crash happened at around 9.52pm on Sunday 23 April.
The drive and passenger of a black Vauxhall Astra died at the scene.
The road re-opened around 4.47am hours this morning.
Constable Rebecca Wylie of the Road Policing Unit said:
Cloud and patchy rain will quickly clear south during the morning introducing brighter but colder conditions.
During the afternoon there will be sunny spells and maybe a few wintry showers, especially over the hills.
Maximum temperature 11 °C.
A haulage firm founded in Carlisle, Eddie Stobart, has been valued at more than half-a-billion pounds.
The company shares, worth £570million, go on sale tomorrow on the Alternative Investment Market.
Stobart's plans to use some of the revenue to purchase another logistics firm, i-Force, for £45million.
Tourism bosses have come up with a new way to entice people into south-west Scotland - by getting them behind the wheel of their car.
Three driving routes have been created to take advantage of the area's outstanding scenery.
Our reporter, Matthew Taylor, went along for a ride: