More than 120 staff and patients from hospitals in Dumfries have now been affected by the winter vomiting bug.
Castle Douglas hospital has been closed to new admissions and transfers, after 15 staff and 5 patients were affected by the bug.
Annan hospital has also been closed after a patient showed symptoms of norovirus.
The latest information from Dumfries and Galloway Royal Infirmary shows that wards 6 and 14 remain closed to new admissions and transfers, while ward 12 is due to re-open.
A total of 65 patients and 39 staff have reported symptoms since the outbreak began last week.