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The Jenna Dempster Superstar Cycle team left Kendal this morning on day six of the cycle challenge.
They hope to arrive in Moffat at around 4pm.
They are hoping to complete their journey on 28th September.
Seven men from Dumfries are taking part in a mammoth charity cycle in memory of Jenna Demspter, who died from meningitis ten years ago.
The group are cycling more than 1,000 miles during the Land's End to John O'Groats challenge.
The men are currently in Cumbria and are hoping to arrive in Moffat at around 4pm this afternoon, where they will be greeted by friends and family.
Jenna Dempster was 17-years-old when she became ill and was taken to hospital. She was diagnosed with meningitis and died six hours later.
Jenna's brother Daniel is joining the team for the last leg of the route, and will cross the finish with them in John O'Groats.
Alison, Daniel and Jenna's mum, says she struggles to sum up what it means:
"Sometimes I struggle to find the words to describe how I feel. What the boys are doing is absolutely amazing and I'm so proud. Myself, my husband John and Daniel can't wait to welcome them into Scotland."
The group have been spent the last six months training, often cycling 60 miles a day, and have been on special nutritional diets in preparation for the cycle.
Gary McCormick, who organised the "Jenna Dempster Superstar Cycle Challenge", said the support they have had from friends and family has been unbelievable:
"We have had help with the bikes, transport, physiotherapists, everything. The support we have had from friends and family has been unreal.
"We want to raise as much money and awareness for meningitis research as possible."
They have so far raised around £5,000 for Meningitis Research.
Colm Farrell, from County Galway, is walking 5000 miles through the UK to raise money for charity is in the borders this weekend.
He has arrived in Innerleithen and is about to head for Peebles.
A man who is walking 5000 miles through the UK to raise money for charity is in the borders this weekend.
Colm Farrell, who is known as 'the Hazard', has taken on the challenge to support the suicide prevention charity Console.
Colm, who comes from County Galway in Ireland, carries a tent for emergencies but relies on the goodwill of people he meets on his journey for accommodation.
He started his walk in the very north of Scotland in July and he has only needed to stay in his tent once.
He will reach Peebles this afternoon, but his whole journey is expected to take eleven months to complete.
A father from Cumbria has set out on a fundraising cycle ride from Kendal to France, to raise money for the French hospital that saved his baby's life.
Chris Warren's son Bradley was born prematurely when his parents were on holiday - at the time Bradley Wiggins won the Tour de France.
So far, Chris has raised £6,500.
Cumbrian father Chris Warren is setting off on a 5 day cycle ride to France.
He is raising money for the hospital and charities that saved his son's life earlier this year.
Bradley was born 3 months premature when his parents were on holiday in France at the time Bradley Wiggins won the Tour de France.
Chris left Kendal at 9am this morning. He will do 120 miles a day.
A Cumbrian man is cycling to France to raise money for the hospital and staff that delivered his son and saved his life.
Bradley Warren was born early with serious complications while his parents were on holiday in France.
He is now a year old and fit and healthy.
A charity has helped cancer patients in the Borders claim more than £5 million in benefits over the past four years.
One woman who was helped by the Macmillan advice team went bankrupt because of the cost of coping with her disease.
Derek Proud reports:
A man who suffered a heart attack while walking down a mountain in the Lake District will tackle his final charity fundraiser today.
Darren Tate will cycle from Carlisle to Workington to complete his fundraising for the Cumberland Infirmary.
His charity events have included cycling the equivalent of the length of Britain and walking the length of Hadrian's Wall.