Delays of up to 50 minutes can be expected on trains between Carlisle and Preston due to a signalling problem between Oxenholm Lake District and Penrith.
There has been an angry reaction to the latest increase in rail fares.
Ticket prices have gone up by an average of 3.9% , meaning regular commuters will now have to shell out hundreds of pounds more, to travel the same distance.
Unions are calling it the Great Train Robbery, saying it's the 10th successive rise, above inflation.
Operators insist the extra money will allow them to improve the rail network.
Watch the full report from Hannah McNulty below.
Stephen Joseph, the Chief Executive of the independent charity, the Campaign for Better Transport joined us in our London studio to discuss the rise in rail fares.
Unions describe 'Great Train Robbery' as rail fares increaseRead the full story ›
Train operators say the rise in rail fares will allow investment in the infrastructure, but the RMT Union say passengers are facing a bleak future.
The Association of Train Operating Companies (ATOC) has defended the way rail companies apply the fare rises that Government policy allows them. While rail fares can only go up by inflation plus 1% that is the average figure which is why some fares have risen by much more today.
Edward Welsh, ATOC spokesman told ITV News: "Just as they might increase them above 4.2% they have to de-crease them elsewhere.
"It's like a traditional pair of kitchen scales. The Government ensures that all the fares come back to 4.2%."
Rail passengers are being hit in the pocket as inflation-busting fare rises take effect.
Regulated fares, which include season tickets, are increasing by an average of 4.2%, with the overall average rise for all tickets being 3.9%
Campaign groups have pointed out today's increase is the 10th successive above-inflation rise, with some rail season ticket holders seeing their fares rise by more than 50% in the last 10 years. Also, the TUC has said that fares have risen far faster than wages since the recession in 2008.
ScotRail fares will rise by 3.9%.
"We have worked hard to keep the increase down to a level that continues to offer value for money. At the same time, our approach enables us to continue to invest in improvements including more and faster services and better facilities atstations and on trains.”
A replacement bus service is running on Northern Rail between Carlisle and Hexham due to an obstruction on the line at Haltwhistle.
All lines are blocked and journey times may be extended by 30 minutes.
Delays of up to 45 minutes on Virgin Trains between Carlisle and Lancaster due to a broken down train at Penrith. A freight train has broken down.
Also affecting First Transpennine Express. There is currently no estimate for normal service.