A three-vehicle crash on one of the main routes into Carlisle is causing traffic disruption throughout the city.
The collision happened on the A7 roundabout at Junction 44 of the M6.
Traffic lights on the roundabout are currently down.
The A7 is closed in the Scottish Borders between Selkirk and Galashiels after a car collided with a gas main.
Two men have been taken to the Borders General Hospital, where they're being treated for their injuries.
Police Scotland say the road will remain closed for some time.
A 12-week-old baby girl was taken to York Hill Sick Kid Hospital in Glasgow with suspected head injuries following a minibus crash in Dumfries and Galloway last night.
She was hurt when a white coloured LDV minibus with a group of eight from Milton Keynes left the A74(M) and overturned at around 5.25pm.
Two girls aged 16 and 13 and three boys aged 12, 10 and 8 were taken to Dumfries and Galloway Royal Infirmary, along with the driver, a 33-year-old man and a 37-year-old male passenger.
All stayed overnight with minor injuries
The incident happened on the southbound carriageway of the Glasgow to Carlisle Road, about 3 miles south of the Greenhill Stairs overbridge at Moffat.
Police Scotland is appealing for witnesses and has asked anyone with information to get in contact.
Dalston Road in Carlisle has been closed after a collision between a pedestrian and a car.
Emergency services are currently at the scene and the road is closed between Richardson Street and Long Sowerby Road.
Diversions are in place along Peter Lane and onto Wigton Road, A595.
Motorists are being asked to avoid the area and use alternative routes.
Dylan Sagar, aged 18 from Holme, was involved in a road traffic collision on the A65 at Millness between the night of Saturday the 14th and the early hours of Sunday 15th December. He died on Friday 20th December 2013 in Preston Hospital from his injuries.
The family of Dylan said:
Police are continuing to investigate the circumstance of the collision, anyone with information should contact PC Davies of Kendal Roads Policing Unit on 101 or Crimestoppers anonymously on 0800 555 111.
A motorcyclist has been airlifted to the James Cook Hospital with serious injuries.
THE A683 between Sedbergh and Kirkby Lonsdale has been closed following a serious accident between Sedbergh and Kirkby Lonsdale. Emergency Services have been called to the road near the Ravenstonedale turning. Police have not yet released any further details.
Hundreds of motorists sweated in the huge traffic jam and many sat out on the barriers and bankings as temperatures soared to 80 degrees
Police, ambulance staff, doctors and firefighters worked at the scene for more than two hours.
Three people were badly hurt after a Range Rover crashed into the concrete upright of a motorway bridge. The three, a man and two women, had to be freed from the wreckage of the vehicle four miles south of Beattock on the northbound carriageway of the A74M.
Firefighters worked at the scene for more than 90 minutes to free the trapped who were said to be badly hurt. Police are still treating the accident as a potential fatal after two air ambulances were sent to the motorway at Junction 15 north of Johnstonebridge.
Police closed both carriageways for two hours and thousands of vehicles were queued back up to six miles. Police set up diversions and later opened one lane on each side of the motorway to let traffic off before closing the northbound lane again for a major accident investigation.
Around 1:30pm hours on Saturday 13 July 2013 a serious crash occurred on the A76 Dumfries to Kilmarnock road at the southern entrance to Drumlanrig Castle involving a car and a motorbike.
The 41 year old rider of the motorbike was taken to hospital by air ambulance suffering from serious injuries. The 80 year old driver of the Citroen was not injured.
Police are appealing for witnesses to the crash or who may have seen either vehicle prior to the collision to contact officers at Thornhill Police Station on 101