A man has been pronounced dead at the scene of the two-car road traffic crash on the A701 road near to Cragielands House in Beattock.
A second man has been taken to Dumfries and Galloway Royal Infirmary with what are thought to be serious injuries, police say.
Police Scotland has confirmed the road at the scene will be closed for some considerable time to allow for a full crash investigation to take place.
Diversions have been put in place; for immediate updates click here.
Police are continuing to investigate a 'serious' incident on Leconfield Street in Cleator Moor.
Officers were called to the scene at 8:12am this morning, Friday 11 July, after reports of a hit and run.
Witnesses said a blue vehicle hit a pedestrian but failed to stop.
The road is closed between The Square and the Co-Op store and all motorists are asked to avoid the area and use alternative routes.
Anyone with any information about the incident is asked to contact the police.
Police say a child who was taken to hospital following a crash in Cumbria is not as badly injured as first thought.
The incident happened on Friday 15th November at around 5pm.
The child is still in hospital care.
A 15-year-old boy has died after being struck by a car in Carlisle. Matthew Hamilton was cycling on Brunel Way at 6 o'clock last night when the collision happened. Police are appealing for witnesses.
The policeman who was killed in a road traffic accident has been named as 38 year old PC Craig Postlethwaite.
He lived in the Workington area and worked in the west Cumbria roads policing unit. He was off duty when the accident happened near Cockermouth on Wednesday afternoon.
Sergeant Jim Lloyd, who worked with Craig and is a close family friend. He said PC Postlethwaite was an exemplary officer and paid tribute to him:
“Craig was an exceptional man and a very dedicated officer. He recently moved to the Roads Policing Unit which was a career path that he had always wanted to follow and had also just completed his firearms course.
He was well liked and respected by the community and all his colleagues – he was a genuinely nice and thoroughly decent bloke. As a police officer, he was an example to us all. He will be a massive loss to the policing family and we will all miss him.”
Witnesses are being sought after an off duty policeman was killed in a road accident in west Cumbria. he was driving a motorbike when he was involved in a collision with a 4 x 4 near Cockermouth.
Cumbria police have confirmed that an off duty policeman has been killed in an accident in west Cumbria.
The accident happened on Wednesday on Lamplugh Road, Cockermouth between a motorbike and 4 x 4 vehicle.
The off duty policeman who was driving the motorbike died at the scene. He was a 38 year old from the Workington area. He hasn't been named. The driver of the car, a 65 year old man from the Penrith area is being treated for shock in the Cumberland Infirmary.