A van driver has been flown to hospital with serious injuries after their vehicle overturned on the M6 northbound carriageway at J44, near Carlisle.
The collision happened at around 8.30am this morning, Thursday 19 April.
The north and southbound carriageways were temporarily closed to allow an air ambulance to land and for the vehicle to be recovered.
The south and northbound carriageways are now fully open.
Two men have been taken to hospital following a serious collision involving two lorries on the A66.
Officers were called to the incident near to Kirkby Thore at around 9.30am.
One driver, a man in his 50s, from Scotland, was taken to Carlisle's Cumberland Infirmary.
Another driver, a man in his 40s, was flown to James Cook University Hospital in Middlesbrough.
Police say the road is expected to be closed for five to six hours, in both directions, between Kemplay Bank and Brough.
A driver has sustained serious injuries after a car and a recovery vehicle collided on the main A7 road in Cumbria, near Longtown.
The accident closed the road for several hours between the A6071 Albert Street and Sandysyke on Tuesday 20 March.
Cumbria Fire & Rescue Service were called to the scene to assist North West Ambulance Service in cutting the driver of the car free.
The driver of the recovery vehicle suffered minor injuries.
Investigations are ongoing and anyone who witnessed the collision is asked to call 101.
The main A7 road in Cumbria was closed for several hours after a serious accident near Longtown.
A car and a recovery vehicle collided between the A6071 Albert Street and Sandysyke.
Fire crews were called to the scene to free a trapped driver. There is yet to be an update on the conditions of those involved.
Police have confirmed the road is now clear and has fully re-opened in both directions.
A 30-year-old man has been taken to hospital with non-serious head injuries following a two-vehicle crash on the A69.
Emergency services were alerted to the incident near Low Row, Carlisle between the A689 and the Denton Mill turn-off at 1.30pm.
The occupants of the second vehicle are not believed to be injured.
All lanes have now been re-opened.
A 92-year-old man from Cockermouth is in a critical condition after being involved in a crash with a lorry on the A66 near Threlkeld yesterday afternoon.
The driver of the lorry was a 46-year-old man from St Helens, who was uninjured.
Police were called at 2.20pm and the road was closed until 8.30pm while emergency services dealt with the incident.
The elderly man was taken to the Royal Victoria Infirmary in Newcastle. An update is expected be given on his condition this afternoon.