Hundreds of golfers are competing in the west Cumbria for the prestigious English Amateur Championship.
The event is being staged at Silloth Golf Club, with some playing at Seascale.
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The historic event always takes place on the last Friday in July.
Early enquiries suggest the men may have taken the drug Blue Valium. Two of them remain in hospital with breathing problems.
More than 8,000 people are expected to attend over the three day event, which starts at 7pm tonight.