Paul Wheelhouse MSP, from Berwickshire, is to join Alex Salmond's new cabinet.
The economist will take over the position of Minister for Environment and Climate Change, as Stewart Stevenson steps down.
As a result of the reshuffle, Deputy First Minister Nicola Sturgeon will take on the new role of spearheading the Scottish Government's independence campaign.
The First Minister said the changes have been made to assist in taking the Programme for Scotland forward, as well as preparing Scotland for the independence referendum in 2014.
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Concerns about the safety of the hospital's PFI building have been raised by the NHS Trust. The fire service says improvements are needed.