The A66 east of Penrith, near Center Parcs, is currently closed while rescue and recovery work takes place following a crash.
Cumbria Police say diversions are in place. Motorists can use the A65 and A69, the A685 can be used at Brough to join the M6 for westbound traffic but height and weight restrictions apply to the route.
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Carlisle have secured their Football League status by beating Plymouth Argyle 2-0 at Brunton Park.
Kerrie brings you Saturday night's forecast
Carlisle are preparing for game that could see them safe from relegation. They welcome Plymouth Argyle to Brunton Park for a 3pm kick-off.