The A75 is currently closed between Annan and Dumfries and is expected to remain closed for up to five hours, after a road accident early this morning.
The westbound diversion route is via A75 at Ladyfield, onto the B7020 to Dalton and Lochmaben, onto the A709 and then to the A75 at Dumfries.
The eastbound diversion is the reverse route.
Police are asking motorists to avoid the area if possible.
More top news
Trail hunting, where a scent is laid for hounds and the hunt to follow, has been widely practised since the 2005 ban on fox hunting.
Dangerous chemicals stored in a laboratory at the nuclear reprocessing plant have now been detonated by an army bomb disposal team.
Explosives experts were called to the nuclear reprocessing site in Cumbria, to help deal with chemical substances.