Black ice has caused a lorry to come off the road near Moffat.
Police say the vehicle has damaged cables which are now hanging down across the road.
It means the A701 is currently closed to high vehicles.
Traffic police are in attendance at the scene.
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The Met Office have issued a yellow "Be Aware" warning of heavy rain for the region which is valid from 3pm Sunday until 3pm Monday
Emma Jesson brings you Saturday night's forecast
Christmas Eve which could be rather frosty, and at present, Christmas Day itself looks like being cold and clear with a few wintry showers