Black ice has caused a lorry to come off the road near Moffat.
Police say the vehicle has damaged cables which are now hanging down across the road.
It means the A701 is currently closed to high vehicles.
Traffic police are in attendance at the scene.
More top news
Nearly half a century ago Donald Campbell died when the boat crashed on Coniston Water. Now, the remains are back on display.
The £2 million lab will be at the centre of a core sciences programme, which the University hopes will meet local and national demand.
A new report has criticised cleanliness and hygiene at Borders General Hospital. NHS Borders says it's already made improvements.