Deputy First Minister Nicola Sturgeon will claim Scotland will be able to build a 'better nation through independence'.
She will speak to business and community leaders at the University of Strathclyde in Glasgow and will address the independence referendum ahead of the vote in 2014.
Nicola Sturgeon is leading the Scottish Governments independence drive. She will set out the core arguments for independence, highlighting the two choices facing the people of Scotland. The SNP administration is describing it as a 'significant speech'.
She said "My conviction that Scotland should be independent stems from the principles, not of identity or nationality, but democracy and social justice. I believe that Scotland has a democratic right to choose our own Government and determine our own future."
The speech starts at 1.45pm.
More top news
A minute's silence will be observed at 11am on Thursday in remembrance of those who lost their lives in the Manchester Arena attack.
A look ahead at the forecast for the Border region.
The 2017 Wool fest is set to take place over two days in June at Cockermouth's Lakeland Livestock Centre.