Deputy First Minister Nicola Sturgeon will claim Scotland will be able to build a 'better nation through independence'.
She will speak to business and community leaders at the University of Strathclyde in Glasgow and will address the independence referendum ahead of the vote in 2014.
Nicola Sturgeon is leading the Scottish Governments independence drive. She will set out the core arguments for independence, highlighting the two choices facing the people of Scotland. The SNP administration is describing it as a 'significant speech'.
She said "My conviction that Scotland should be independent stems from the principles, not of identity or nationality, but democracy and social justice. I believe that Scotland has a democratic right to choose our own Government and determine our own future."
The speech starts at 1.45pm.
More top news
Three girls have been hurt after a stone was thrown through the window of the school bus they were travelling on in Carlisle.
Drivers are being urged to take extreme caution when driving this morning, as heavy snow covers routes across the ITV Border region.
The Met Office has issued a new amber weather warning for snow for the south of Scotland, and a yellow warning for parts of Cumbria.