Harry Cairney's been in charge at Galabank twice, having taken over for the second time in 2006.
He led Annan into the Scottish Football League but now he's decided to step down.
Harry released a statement explaining the pressure of balancing football with his family life and his day job as a teacher was affecting his health.
The Chairman for Annan Athletic, Henry McClelland, paid tribute to the former manager:
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Kerrie brings you Sunday's pollen count
Kerrie brings you Sunday night's forecast
High pressure rebuilds from Monday. Any cloud and rain move westwards. Some low cloud for eastern coasts. Very warm inland