The B5305 is blocked in both directions at Sebergham, Cumbria, as a lorry has jacknifed on Sebergham Bridge.
Delays between Wigton and Penrith can be expected and police say the road will not be clear until at least 10am.
More top news
A look ahead at the forecast for the Border region.
His father, Secretary of State for Scotland David Mundell, is one of the highest profile Remain supporters north of the border.
The company that owns a Cumbrian nursing home has been fined £400,000 after a 91-year-old woman died after falling from her bed.