Around 400 metres of road is covered in glue on the A76, near Sanquhar, after a lorry overturned.
The road is expected to be closed for several hours.
The current diversion is 50 miles long.
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Becoming dry and bright on Saturday, turning colder. Wintry showers possible on Sunday and Monday
A look ahead at the weekend forecast for the Border region - and things are getting colder!