Two riders being transported to hospital. It is not clear at this time the extent of their injuries.
The A686 is currently closed a Melmerby and Alston and motorists are advised to avoid the area and use alternative routes.
More top news
Sunny spells to end Sunday and start Monday - then it's 'all change' with a quite unseasonal weather story into Tuesday
Kerrie brings you Saturday's Pollen for the Border region
Kerrie brings you Saturday's forecast for the Border region