Two riders being transported to hospital. It is not clear at this time the extent of their injuries.
The A686 is currently closed a Melmerby and Alston and motorists are advised to avoid the area and use alternative routes.
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Political Editor Peter MacMahon speaks to Ruth Davidson, who's made the Scottish Tories the largest opposition group at Holyrood.
An additional 53 people, ranging from ages one to 86, are suspected to have been poisoned by raw milk from the farm's vending machine.
RSPB's Big Garden Birdwatch to take place over three days from 28 January. More than half a million people are expected to take part.