Two riders being transported to hospital. It is not clear at this time the extent of their injuries.
The A686 is currently closed a Melmerby and Alston and motorists are advised to avoid the area and use alternative routes.
More top news
Cumbria Police have been praised for the way they work with victims of crime, according to a new report by HMIC.
A mental health ward in Kendal is to remain open until the outcome of a delayed public consultation into its future.
A look ahead at the forecast for the Border region.