The Citizens Advice Service in Dumfries and Galloway has won a grant of £215,939.
The funding, awarded by the Big Lottery, is aimed at helping local people cope with the impact of the government's welfare cuts.
The money will be put towards developing more expert advice across the region over the next 18 months.
AnnaN, Upper Nithsdale, North West Dumfries and Stranraer West are the four areas that have been identified as having particularly bad problems.
These areas will be offered a home-visiting advice service to vulnerable clients, and four advisers will be employed to work with local support agencies to prevent people falling below the poverty line.