Mo Farah and Haile Gebrselassie will battle it out at the front of the race, but every single one of the runners that cross the Tyne Bridge on Sunday will have their own story to tell.
Gemma Carter is one of them and she is following in the footsteps of her father who now has Motor Neurone Disease, the charity Gemma is running for.
Fiona Marley Paterson went to meet them - watch her full report below.
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The family of Christian Pay, who died on Friday after suspected substance abuse at a festival, have paid tribute to the Millom teenager.
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Christian Pay's family say he was "loved by all" and had "the heart of a lion". The 18-year-old died after falling ill at the festival.