Mo Farah and Haile Gebrselassie will battle it out at the front of the race, but every single one of the runners that cross the Tyne Bridge on Sunday will have their own story to tell.
Gemma Carter is one of them and she is following in the footsteps of her father who now has Motor Neurone Disease, the charity Gemma is running for.
Fiona Marley Paterson went to meet them - watch her full report below.
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Emma brings you Saturday's forecast
Longest cold spell of winter so far. Mainly dry and bright, but feeling bitterly cold today. Very wintry further east, blizzards possible
Mountain Rescue has seen a 5% increase in rescues and with the current conditions they're advising people to take extra care.