The Border region could be hardest hit if Scotland becomes independent, according to the Deputy Prime Minister.
Speaking at the Liberal Democrat conference in Glasgow, he told ITV News that a 'yes' vote this time next year would destroy trade in the region.
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Political leaders will go head-to-head at ITV's studios in MediaCityUK in Salford, ITV has confirmed, as the set for the event is unveiled.
A look ahead at the forecast for the Border region.
Katy Miles and her mother have abseiled down Yorkhill Hospital to raise money for charity.