The A66 has been closed at Threlkeld following a collision involving a car and a cyclist.
Emergency services are currently at the scene at the junction with Threlkeld, near Keswick.
The extent of the cyclist's injuries are not known at this time.
Motorists are being advised to avoid the area and to seek alternative routes.
More top news
Storm Doris is set to bring wet, windy and wintry weather to the region.
Carl Hodgson, who lives in the town, was sentenced to three years and six months behind bars at Manchester Crown Court today.
The group fears a hoard of Viking treasure found in the region will be moved to the national museum in Edinburgh.